PTK7 抗体 (C-Term)
Quick Overview for PTK7 抗体 (C-Term) (ABIN2854472)
抗原
See all PTK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to CCK4 (CCK4 protein tyrosine kinase 7)
CCK4 antibody [C1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human CCK4. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.36 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma." in: Cancer research, Vol. 74, Issue 10, pp. 2892-902, (2014) (PubMed).
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A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma." in: Cancer research, Vol. 74, Issue 10, pp. 2892-902, (2014) (PubMed).
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- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
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别名
- protein tyrosine kinase 7 (inactive)
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背景
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Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein -
分子量
- 118 kDa
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基因ID
- 5754
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UniProt
- Q13308
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途径
- RTK signaling, Tube Formation
抗原
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