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C4BPB 抗体

This anti-C4BPB antibody is a 兔 多克隆 antibody detecting C4BPB in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2854461
发货至: 中国

Quick Overview for C4BPB 抗体 (ABIN2854461)

抗原

See all C4BPB 抗体
C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

适用

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宿主

  • 34
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克隆类型

  • 35
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多克隆

标记

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This C4BPB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    产品特性

    Rabbit Polyclonal antibody to C4 binding protein B (complement component 4 binding protein, beta)
    C4 binding protein B antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human C4 binding protein B. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Jurkat , Raji , K562 , BCL-1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

    别名

    complement component 4 binding protein beta

    背景

    This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

    Cellular Localization: Secreted

    分子量

    28 kDa

    基因ID

    725

    UniProt

    P20851

    途径

    Complement System
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