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UNG 抗体

Cited in 1 publication. This 兔 多克隆 anti-UNG antibody specifically detects UNG in WB 和 IHC (wm). The antibody is reactive with 人 samples.
产品编号 ABIN2854428
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for UNG 抗体 (ABIN2854428)

抗原

See all UNG 抗体
UNG (Uracil-DNA Glycosylase (UNG))

适用

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宿主

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克隆类型

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多克隆

标记

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This UNG antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Whole Mount) (IHC (wm))
  • 交叉反应

    人, 斑马鱼

    产品特性

    Rabbit Polyclonal antibody to UNG (uracil-DNA glycosylase)
    UNG antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human UNG. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Wu, Chen, Sun, Wu, Jia, Meng: "Uracil-DNA glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo." in: The Journal of biological chemistry, Vol. 289, Issue 22, pp. 15463-73, (2014) (PubMed).

  • 抗原

    UNG (Uracil-DNA Glycosylase (UNG))

    别名

    uracil DNA glycosylase

    背景

    This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2.

    Cellular Localization: Isoform 1: Mitochondrion , Isoform 2: Nucleus

    分子量

    35 kDa

    基因ID

    7374

    UniProt

    P13051

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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