LIG1 抗体 (C-Term)
(1 reference)Quick Overview for LIG1 抗体 (C-Term) (ABIN2854412)
抗原
See all LIG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to DNA ligase I (ligase I, DNA, ATP-dependent)
DNA ligase I antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human DNA ligase I. The exact sequence is proprietary.
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亚型
- IgG
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anti-Ligase I, DNA, ATP-Dependent (LIG1) antibody
LIG1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) (AA 810-919) antibodyLIG1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal AG12 unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) (AA 565-790) antibodyLIG1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) antibodyLIG1 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 7B2 unconjugated Recombinant Antibody
anti-Ligase I, DNA, ATP-Dependent (LIG1) (Internal Region) antibodyLIG1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) (AA 1-919) antibodyLIG1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) antibodyLIG1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) (AA 810-920) antibodyLIG1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 10G12 unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) antibodyLIG1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ligase I, DNA, ATP-Dependent (LIG1) (AA 568-875) antibodyLIG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , H1299
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase." in: Nucleic acids research, Vol. 47, Issue 5, pp. 2402-2424, (2019) (PubMed).
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: "DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase." in: Nucleic acids research, Vol. 47, Issue 5, pp. 2402-2424, (2019) (PubMed).
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- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
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别名
- DNA ligase 1
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背景
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LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
Cellular Localization: Nucleus -
分子量
- 102 kDa
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基因ID
- 3978
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UniProt
- P18858
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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