RAP1A 抗体 (Center)
Quick Overview for RAP1A 抗体 (Center) (ABIN2854404)
抗原
See all RAP1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应
- 小鼠, 大鼠, 猕猴, 牛
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交叉反应 (详细)
- Mouse (100 %), Rat (100 %), Rhesus Monkey (100 %), Bovine (100 %)
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产品特性
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Rabbit polyclonal antibody to RAP1A (RAP1A, member of RAS oncogene family)
RAP1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human RAP1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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说明
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Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.53 mg/mL
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缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells." in: Cancers, Vol. 14, Issue 9, (2022) (PubMed).
: "
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TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells." in: Cancers, Vol. 14, Issue 9, (2022) (PubMed).
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- RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
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别名
- RAP1
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背景
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The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Cellular Localization: Cell membrane, Lipid-anchor -
分子量
- 21 kDa
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基因ID
- 5906
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途径
- TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
抗原
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