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FAP 抗体

This anti-FAP antibody (ABIN2854402) is a Rabbit Polyclonal antibody detecting FAP in WB. Suitable for Human.
产品编号 ABIN2854402
发货至: 中国

Quick Overview for FAP 抗体 (ABIN2854402)

抗原

See all FAP 抗体
FAP (Fibroblast Activation Protein, alpha (FAP))

适用

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宿主

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克隆类型

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多克隆

标记

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This FAP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    产品特性

    Rabbit polyclonal antibody to FAP (fibroblast activation protein, alpha)
    FAP antibody [N1N3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human FAP. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2 , Molt-4

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.58 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Wolczyk, Zaremba-Czogalla, Hryniewicz-Jankowska, Tabola, Grabowski, Sikorski, Augoff: "TNF-α promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts." in: Cellular oncology (Dordrecht), Vol. 39, Issue 4, pp. 353-63, (2017) (PubMed).

  • 抗原

    FAP (Fibroblast Activation Protein, alpha (FAP))

    别名

    fibroblast activation protein alpha

    背景

    The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

    Cellular Localization: Cell membrane, Single-pass type II membrane protein , Cell projection , lamellipodium membrane, Single-pass type II membrane protein , invadopodium membrane, Single-pass type II membrane protein

    分子量

    88 kDa

    基因ID

    2191

    UniProt

    Q12884

    途径

    Tube Formation
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