NUP98 抗体
Quick Overview for NUP98 抗体 (ABIN2854401)
抗原
See all NUP98 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 猴
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产品特性
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Rabbit polyclonal antibody to NUP98 (nucleoporin 98 kDa)
NUP98 antibody [N1N2], N-term -
纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human NUP98. The exact sequence is proprietary.
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亚型
- IgG
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anti-Nucleoporin 98kDa (NUP98) (AA 1-466) antibody
NUP98 适用: 人, 小鼠, 大鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IF, ICC, DB 宿主: 大鼠 Monoclonal 2H10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (GLFG Motif), (N-Term) antibodyNUP98 适用: 人, 小鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 21A10 unconjugated
anti-Nucleoporin 98kDa (NUP98) (FGxxN Motif), (N-Term) antibodyNUP98 适用: 人, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena WB, IF 宿主: 小鼠 Monoclonal 13C2 unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 965-1110) antibodyNUP98 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Nucleoporin 98kDa (NUP98) (AA 621-920) antibodyNUP98 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-606) antibodyNUP98 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) antibodyNUP98 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 98kDa (NUP98) (AA 1-110) antibodyNUP98 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: cos 7
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.39 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- NUP98 (Nucleoporin 98kDa (NUP98))
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别名
- nucleoporin 98
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背景
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Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kD precursor protein. This cleavage results in the 98 kD nucleoporin as well as a 96 kD nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
Cellular Localization: Nucleus , nuclear pore complex , Nucleus membrane, Peripheral membrane protein, Nucleoplasmic side -
分子量
- 198 kDa
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基因ID
- 4928
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UniProt
- P52948
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途径
- Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
抗原
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