ILK 抗体
(1 reference)Quick Overview for ILK 抗体 (ABIN2854345)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 小鼠, 大鼠, 斑马鱼
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产品特性
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Rabbit Polyclonal antibody to CKR5 (integrin-linked kinase)
ILK antibody [N1C1] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ILK. The exact sequence is proprietary.
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亚型
- IgG
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anti-Integrin-Linked Kinase (ILK) (AA 97-244) antibody
ILK 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 341-452) antibodyILK 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 301-400) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-260) antibodyILK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 225-253) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 11-41) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (pThr173) antibodyILK 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-228) antibodyILK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (C-Term) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) antibodyILK 适用: 人 WB, ELISA, IP, IF 宿主: 兔 Monoclonal 6A5 unconjugated Recombinant Antibody
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , Neuro2A , C8D30 , NIH-3T3 , C2Cl2 , PC-12 , Neuro 2A , C8D30 , Raw264.7 , HeLa
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.8 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin ..." in: Oncotarget, Vol. 6, Issue 39, pp. 41837-55, (2016) (PubMed).
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: "Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin ..." in: Oncotarget, Vol. 6, Issue 39, pp. 41837-55, (2016) (PubMed).
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- integrin linked kinase
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背景
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Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Cellular Localization: Cell junction , focal adhesion , Cell membrane, Peripheral membrane protein, Cytoplasmic side -
分子量
- 51 kDa
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基因ID
- 3611
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UniProt
- Q13418
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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