SNAIL 抗体
(4 references)Quick Overview for SNAIL 抗体 (ABIN2854294)
抗原
See all SNAIL (SNAI1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to SNAI1 (snail family zinc finger 1)
SNAI1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human SNAI1. The exact sequence is proprietary.
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亚型
- IgG
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anti-SNAIL (SNAI1) (AA 1-100) antibody
SNAI1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (C-Term) antibodySNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (C-Term) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (N-Term) antibodySNAI1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 121-230) antibodySNAI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-SNAIL (SNAI1) (AA 1-264) antibodySNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 9-39), (N-Term) antibodySNAI1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01400 unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (pSer246) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , HeLa (starvation for 16 hr 20 ng/ml TGF-beta and 300 ng/ml EGF treatment for 30 min) , SNAI1-transfected 293T
Validation: Comparison, Orthogonal, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.54 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer." in: International journal of molecular sciences, Vol. 21, Issue 14, (2020) (PubMed).
: "Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis." in: Oncotarget, Vol. 8, Issue 21, pp. 34205-34222, (2018) (PubMed).
: "NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition." in: Oncogene, Vol. 35, Issue 17, pp. 2266-78, (2017) (PubMed).
: "Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells." in: Scientific reports, Vol. 7, pp. 41437, (2017) (PubMed).
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: "NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer." in: International journal of molecular sciences, Vol. 21, Issue 14, (2020) (PubMed).
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- SNAIL (SNAI1)
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别名
- snail family transcriptional repressor 1
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背景
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The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
Cellular Localization: Nucleus -
分子量
- 29 kDa
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基因ID
- 6615
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UniProt
- O95863
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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