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PLAU 抗体 (N-Term)

This anti-PLAU antibody is a 兔 多克隆 antibody detecting PLAU in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN2853629
发货至: 中国

Quick Overview for PLAU 抗体 (N-Term) (ABIN2853629)

抗原

See all PLAU 抗体
PLAU (Plasminogen Activator, Urokinase (PLAU))

适用

  • 86
  • 28
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  • 7
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  • 1
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  • 1
人, 小鼠

宿主

  • 86
  • 20
  • 12
  • 5
  • 1
  • 1

克隆类型

  • 90
  • 31
  • 2
多克隆

标记

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  • 10
  • 4
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  • 2
  • 2
  • 2
  • 2
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  • 1
This PLAU antibody is un-conjugated

应用范围

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  • 27
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  • 12
  • 10
  • 10
  • 9
  • 6
  • 3
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 68-98, N-Term

    特异性

    This antibody recognizes Urokinase/PLAU (N-term).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between aa 68-98 from the N-terminal region of human PLAU.
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09% (w/v) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

    有效期

    12 months
  • 抗原

    PLAU (Plasminogen Activator, Urokinase (PLAU))

    别名

    uPA / PLAU

    背景

    PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.
    Alternate names: U-plasminogen activator, Urokinase, Urokinase-type plasminogen activator, Urokinase- type plasminogen activator chain B, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A

    基因ID

    5328, 9606

    UniProt

    P00749

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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