PD-L1 抗体 (Biotin)
-
- 抗原 See all PD-L1 抗体
- PD-L1 (CD274 (PD-L1))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This PD-L1 antibody is conjugated to Biotin
-
应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody reacts with human CD274.
- 纯化方法
- Protein A agarose
- 免疫原
- Full-length human PD-L1 transfected L cells
- 克隆位点
- MIH3
- 亚型
- IgG1
- Top Product
- Discover our top product PD-L1 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 0.02 mg/mL
- 缓冲液
- PBS, 0.09 % NaN3, 1 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 2 - 8 °C.
-
- 抗原
- PD-L1 (CD274 (PD-L1))
- 别名
- CD274 / PDL1 (PD-L1 产品)
- 背景
- Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunoglobulin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitro study indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-γ, GM-CSF and IL-10 from the T cells were enhanced.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
- 基因ID
- 29126
- NCBI登录号
- NP_054862
- UniProt
- Q9NZQ7
- 途径
- Cancer Immune Checkpoints
-