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PD-L1 抗体 (Biotin)

This anti-PD-L1 antibody is a 小鼠 单克隆 antibody detecting PD-L1 in FACS. Suitable for 人.
产品编号 ABIN2853592
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PD-L1 抗体 (Biotin) (ABIN2853592)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PD-L1 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

MIH3
  • 特异性

    This antibody reacts with human CD274.

    纯化方法

    Protein A agarose

    免疫原

    Full-length human PD-L1 transfected L cells

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.02 mg/mL

    缓冲液

    PBS, 0.09 % NaN3, 1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 2 - 8 °C.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    CD274 / PDL1

    背景

    Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunoglobulin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitro study indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-γ, GM-CSF and IL-10 from the T cells were enhanced.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1

    基因ID

    29126

    NCBI登录号

    NP_054862

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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