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Cyclin A 抗体 (Biotin)

CCNA2 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 小鼠 Monoclonal E67-1 Biotin
产品编号 ABIN2853583
发货至: 中国
  • 抗原 See all Cyclin A (CCNA2) 抗体
    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 59
    • 33
    • 1
    小鼠
    克隆类型
    • 48
    • 45
    单克隆
    标记
    • 67
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    This Cyclin A antibody is conjugated to Biotin
    应用范围
    • 56
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    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    This antibody reacts with Cyclin A (55 kDa).
    纯化方法
    Protein-A Agarose Chromatography of hybridoma supernatant.
    免疫原
    Bovine recombinant Cyclin A.
    克隆位点
    E67-1
    亚型
    IgG2a
    Top Product
    Discover our top product CCNA2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    20 µg/mL
    缓冲液
    PBS, pH 7.2 containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
    别名
    Cyclin A2 (CCNA2 产品)
    别名
    CCN1 antibody, CCNA antibody, AA408589 antibody, Ccn-1 antibody, Ccn1 antibody, Ccna antibody, CycA2 antibody, Cyca antibody, cb671 antibody, chunp6924 antibody, wu:fi36f03 antibody, CYCA antibody, Cyclin-A2 antibody, ccna2 antibody, ccn1 antibody, ccna antibody, ccna1 antibody, Cyclin-A antibody, cyclinA antibody, cyclin A2 antibody, cyclin A2 S homeolog antibody, cyclin A2 L homeolog antibody, CCNA2 antibody, Ccna2 antibody, ccna2 antibody, ccna2.S antibody, ccna2.L antibody
    背景
    Cyclin A is a 60 kDa cyclin that binds both cdk2 and p34cdc2 (cdk1), giving two distinct cyclin A kinase activities, one appearing in G1/S phase, the other in G2/M. The level of cyclin A protein peaks in S-phase, and the activity of the cdk2-cyclin A complexes is essential for DNA replication and progression through S phase. Cyclin A is thus a marker for actively proliferating cells and for cells in S-phase. In normal cells, cdk2-cyclin A complexes associate with PCNA and p21CIPP1/WAF1. In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcrIPPtion factors DRT F1 and E2F, and retinoblastoma protein, p110.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
    基因ID
    890
    NCBI登录号
    NP_001228
    UniProt
    P20248
    途径
    PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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