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FOXA2 抗体 (AA 201-300) (AbBy Fluor® 594)

This AbBy Fluor® 594-conjugated 兔 多克隆 anti-FOXA2 antibody specifically detects FOXA2 in WB, FACS, IF (cc) 和 IF (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN2808614
发货至: 中国
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Quick Overview for FOXA2 抗体 (AA 201-300) (AbBy Fluor® 594) (ABIN2808614)

抗原

See all FOXA2 抗体
FOXA2 (Forkhead Box A2 (FOXA2))

适用

  • 99
  • 27
  • 16
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
人, 小鼠

宿主

  • 87
  • 14
  • 2

克隆类型

  • 71
  • 32
多克隆

标记

  • 53
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXA2 antibody is conjugated to AbBy Fluor® 594

应用范围

  • 88
  • 40
  • 34
  • 31
  • 20
  • 19
  • 13
  • 12
  • 12
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 9
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HNF 3 beta

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FOXA2 (Forkhead Box A2 (FOXA2))

    别名

    FOXA2/ HNF 3beta

    背景

    Synonyms: HNF3B, TCF3B, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, Forkhead box protein A2, Transcription factor 3B, TCF-3B, FOXA2

    Background: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs, FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.

    基因ID

    3170

    UniProt

    Q9Y261

    途径

    Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
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