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Dihydrofolate Reductase 抗体 (AbBy Fluor® 594)

This anti-Dihydrofolate Reductase antibody is a 兔 多克隆 antibody detecting Dihydrofolate Reductase in IF (p). Suitable for 人 和 小鼠.
产品编号 ABIN2808570
发货至: 中国

Quick Overview for Dihydrofolate Reductase 抗体 (AbBy Fluor® 594) (ABIN2808570)

抗原

See all Dihydrofolate Reductase (DHFR) 抗体
Dihydrofolate Reductase (DHFR)

适用

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人, 小鼠

宿主

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克隆类型

  • 43
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多克隆

标记

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This Dihydrofolate Reductase antibody is conjugated to AbBy Fluor® 594

应用范围

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  • 20
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Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DHFR

    亚型

    IgG
  • 应用备注

    FCM(1:20-100), IF(IHC-P)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4°C

    有效期

    12 months
  • 抗原

    Dihydrofolate Reductase (DHFR)

    别名

    DHFR

    背景

    DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.


    Synonyms: DHFR, DHFRP1, Dihydrofolate reductase, DYR, DYR_HUMAN, EC 1.5.1.3.

    基因ID

    1719

    途径

    Mitotic G1-G1/S Phases
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