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TNRC6B 抗体 (AA 25-70) (AbBy Fluor® 594)

This AbBy Fluor® 594-conjugated 兔 多克隆 anti-TNRC6B antibody specifically detects TNRC6B in WB, IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN2807121
发货至: 中国
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Quick Overview for TNRC6B 抗体 (AA 25-70) (AbBy Fluor® 594) (ABIN2807121)

抗原

See all TNRC6B 抗体
TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

适用

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宿主

  • 25
  • 2

克隆类型

  • 25
  • 2
多克隆

标记

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This TNRC6B antibody is conjugated to AbBy Fluor® 594

应用范围

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  • 3
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 25-70

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TNRC6B

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

    别名

    TNRC6B

    背景

    Synonyms: KIAA1093, TNRC 6B, Trinucleotide repeat containing 6B, Trinucleotide repeat containing gene 6B protein, TNR6B_HUMAN.

    Background: TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway
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