OGG1 抗体 (AA 151-250) (AbBy Fluor® 594)
Quick Overview for OGG1 抗体 (AA 151-250) (AbBy Fluor® 594) (ABIN2804874)
抗原
See all OGG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human OGG1/8 hydroxyguanine DNA glycosylase
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亚型
- IgG
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
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别名
- OGG1
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背景
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Synonyms: 8 hydroxyguanine DNA glycosylase, 8 oxoguanine DNA glycosylase 1, 8-oxoguanine DNA glycosylase, AP lyase, DNA apurinic or apyrimidinic site lyase, DNA lyase, DNA-apurinic or apyrimidinic site lyase, HMMH, HOGG 1, HOGG1, MMH, MUTM, N-glycosylase, Ogg 1, OGH 1, OGH1, OGG1_HUMAN.
Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008].
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基因ID
- 4968
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途径
- DNA Damage Repair
抗原
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