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MSH3 抗体 (AA 651-750) (AbBy Fluor® 594)

This anti-MSH3 antibody is a 兔 多克隆 antibody detecting MSH3 in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN2804316
发货至: 中国

Quick Overview for MSH3 抗体 (AA 651-750) (AbBy Fluor® 594) (ABIN2804316)

抗原

See all MSH3 抗体
MSH3 (MutS Homolog 3 (MSH3))

适用

  • 27
  • 3
  • 2

宿主

  • 27

克隆类型

  • 27
多克隆

标记

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MSH3 antibody is conjugated to AbBy Fluor® 594

应用范围

  • 12
  • 12
  • 12
  • 9
  • 6
  • 4
  • 4
  • 4
  • 4
  • 2
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 651-750

    预测反应

    Human,Mouse,Rat,Dog,Cow,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MSH3

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MSH3 (MutS Homolog 3 (MSH3))

    别名

    MSH3

    背景

    Synonyms: Divergent upstream protein, DNA mismatch repair protein, DNA mismatch repair protein Msh 3, DNA mismatch repair protein Msh3, DUC 1, DUC1, DUG, DUP, hMSH3, Mismatch repair protein 1, MRP 1, MRP1, MSH 3, MSH-3, MSH3_HUMAN, MutS homolog 3.

    Background: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

    基因ID

    4437

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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