TLR2 抗体 (C-Term)
Quick Overview for TLR2 抗体 (C-Term) (ABIN2800624)
抗原
See all TLR2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 720-749, C-Term
-
原理
- Rabbit Anti-Mouse TLR2 (C-term) Antibody
-
免疫原
- This Mouse TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-749 amino acids from the C-terminal region of mouse TLR2.
-
亚型
- Ig Fraction
-
-
anti-Toll-Like Receptor 2 (TLR2) (AA 720-749) antibody
TLR2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 2 (TLR2) (AA 212-242) antibodyTLR2 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 2 (TLR2) antibodyTLR2 适用: 人 WB 宿主: 小鼠 Monoclonal 1070CT4-2-3-2 unconjugated
anti-Toll-Like Receptor 2 (TLR2) (AA 281-310) antibodyTLR2 适用: 人 WB 宿主: 兔 Polyclonal RB33608 unconjugated
-
-
应用备注
-
Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-TLR2 Pab (102-12774) pre-incubated without and with blocking peptide (BP#1502c) in CEM cell line lysate. TLR2-V735(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Mouse Tlr2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 2.0 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- TLR2 (Toll-Like Receptor 2 (TLR2))
-
别名
- TLR2
-
背景
-
Target Description: TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Gene Symbol: Tlr2
-
分子量
- 89449 Da
-
基因ID
- 24088
-
UniProt
- Q9QUN7
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
-
