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HDAC9 抗体 (C-Term)

This anti-HDAC9 antibody is a 兔 多克隆 antibody detecting HDAC9 in WB, IHC 和 IP. Suitable for 人.
产品编号 ABIN2800619
发货至: 中国

Quick Overview for HDAC9 抗体 (C-Term) (ABIN2800619)

抗原

See all HDAC9 抗体
HDAC9 (Histone Deacetylase 9 (HDAC9))

适用

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宿主

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克隆类型

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多克隆

标记

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This HDAC9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 抗原表位

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    AA 503-533, C-Term

    原理

    Rabbit Anti-Human HDAC9 (C-term) Antibody

    免疫原

    This HDAC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-533 amino acids from the C-terminal region of human HDAC9.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100Both anti-HDAC9 N-term (102-10933) and C-term (102-10934) Pab were tested by WB and IP-WB using HeLa and HeLa-HDAC9 transfected cells. Top figure shows both Pab specifically detect HDAC9 in HeLa-HDAC9 transfected cell but not HeLa alone. Bottom figure shows that both Pab can immunoprecipitate (IP) HDAC9 from HeLa-HDAC9 tranfected cells. (Data kindly provided by Dr. Zhigang Yuan, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL).
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.000 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    HDAC9 (Histone Deacetylase 9 (HDAC9))

    别名

    HDAC9

    背景

    Target Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

    Gene Symbol: HDAC9

    分子量

    111297 Da

    基因ID

    9734

    UniProt

    Q9UKV0

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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