EPO 抗体 (Center)
Quick Overview for EPO 抗体 (Center) (ABIN2799146)
抗原
See all EPO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 329-357, Center
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原理
- Rabbit Anti-Human EPOR (Center) Antibody
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免疫原
- This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50EPOR Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.300 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- EPO (Erythropoietin (EPO))
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别名
- EPO
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物质类
- Hormone
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背景
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Target Description: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Gene Symbol: EPOR
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分子量
- 55065 Da
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基因ID
- 2057
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UniProt
- P19235
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途径
- JAK/STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
抗原
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