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BAG4 抗体 (C-Term)

This anti-BAG4 antibody is a 兔 多克隆 antibody detecting BAG4 in WB. Suitable for 人.
产品编号 ABIN2799014
发货至: 中国

Quick Overview for BAG4 抗体 (C-Term) (ABIN2799014)

抗原

See all BAG4 抗体
BAG4 (BCL2-Associated Athanogene 4 (BAG4))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAG4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 381-409, C-Term

    原理

    Rabbit Anti-Human BAG4 (C-term) Antibody

    免疫原

    This BAG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-409 amino acids from the C-terminal region of human BAG4.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot
    Recommended Dilutions
    WB: 1:1000BAG4 Antibody (C-term) .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    BAG4 (BCL2-Associated Athanogene 4 (BAG4))

    别名

    BAG4

    背景

    Target Description: BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.

    Gene Symbol: BAG4

    分子量

    49594 Da

    基因ID

    9530

    UniProt

    O95429

    途径

    Regulation of Actin Filament Polymerization
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