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Integrin beta 7 抗体 (C-Term)

This anti-Integrin beta 7 antibody is a 兔 多克隆 antibody detecting Integrin beta 7 in WB. Suitable for 人.
产品编号 ABIN2798921
发货至: 中国

Quick Overview for Integrin beta 7 抗体 (C-Term) (ABIN2798921)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

适用

  • 69
  • 23
  • 1
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宿主

  • 50
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  • 7
  • 4
  • 1

克隆类型

  • 51
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  • 2
多克隆

标记

  • 36
  • 7
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  • 2
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  • 2
  • 2
  • 2
  • 1
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  • 1
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This Integrin beta 7 antibody is un-conjugated

应用范围

  • 40
  • 22
  • 22
  • 13
  • 13
  • 8
  • 7
  • 7
  • 4
  • 4
  • 4
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  • 3
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 15
    • 8
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    • 4
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    • 1
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    AA 737-765, C-Term

    原理

    Rabbit Anti-Human ITGB7 (C-term) Antibody

    免疫原

    This ITGB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 amino acids from the C-terminal region of human ITGB7.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot
    Recommended Dilutions
    WB: 1:1000ITGB7 Antibody (C-term) .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    ITGB7

    背景

    Target Description: Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

    Gene Symbol: ITGB7

    分子量

    86903 Da

    基因ID

    3695

    UniProt

    P26010

    途径

    Integrin Complex
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