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TLR6 抗体 (C-Term)

This anti-TLR6 antibody is a 兔 多克隆 antibody detecting TLR6 in WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN2798862
发货至: 中国

Quick Overview for TLR6 抗体 (C-Term) (ABIN2798862)

抗原

See all TLR6 抗体
TLR6 (Toll-Like Receptor 6 (TLR6))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLR6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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    AA 393-423, C-Term

    原理

    Rabbit Anti-Human TLR6 (C-term) Antibody

    免疫原

    This TLR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-423 amino acids from the C-terminal region of human TLR6.

    亚型

    Ig Fraction
  • 应用备注

    Flow Cytometry, Western Blot, Immunohistochemistry
    Recommended Dilutions
    FC: 1:10-50, WB: 1:1000, IHC: 1:50-100Flow cytometric analysis of NCI-H460 cells using TLR6 Antibody (C-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.Western blot analysis of anti-TLR6 Pab , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.0 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    TLR6 (Toll-Like Receptor 6 (TLR6))

    别名

    TLR6

    背景

    Target Description: TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.

    Gene Symbol: TLR6

    分子量

    91880 Da

    基因ID

    10333

    UniProt

    Q9Y2C9

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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