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TLR3 抗体

This anti-TLR3 antibody is a 兔 多克隆 antibody detecting TLR3 in WB 和 IHC. Suitable for 人.
产品编号 ABIN2798861
发货至: 中国

Quick Overview for TLR3 抗体 (ABIN2798861)

抗原

See all TLR3 抗体
TLR3 (Toll-Like Receptor 3 (TLR3))

适用

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宿主

  • 89
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克隆类型

  • 92
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多克隆

标记

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This TLR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    Rabbit Anti-Human TLR3 Antibody

    免疫原

    This TLR3 antibody is generated from rabbits immunized with TLR3 recombinant protein.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100Western blot analysis of TLR3 Antibody was detected using the purified Pab.
    Formalin-fixed and paraffin-embedded mouse brain tissue reacted with TLR3 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    TLR3 (Toll-Like Receptor 3 (TLR3))

    别名

    TLR3

    背景

    Target Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.

    Gene Symbol: TLR3

    分子量

    103829 Da

    基因ID

    7098

    UniProt

    O15455

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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