POLG 抗体 (C-Term)
Quick Overview for POLG 抗体 (C-Term) (ABIN2798829)
抗原
See all POLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1120-1148, C-Term
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原理
- Rabbit Anti-Mouse POLG (C-term) Antibody
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免疫原
- This POLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1120-1148 amino acids from the C-terminal region of human POLG.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50, IHC: 1:10-50POLG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.460 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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别名
- POLG
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背景
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Target Description: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
Gene Symbol: POLG
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分子量
- 139562 Da
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基因ID
- 5428
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UniProt
- P54098
抗原
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