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POLG 抗体 (C-Term)

This anti-POLG antibody is a 兔 多克隆 antibody detecting POLG in WB, IHC, IF 和 FACS. Suitable for 小鼠.
产品编号 ABIN2798829
发货至: 中国
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Quick Overview for POLG 抗体 (C-Term) (ABIN2798829)

抗原

See all POLG 抗体
POLG (Polymerase (DNA Directed), gamma (POLG))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This POLG antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
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    AA 1120-1148, C-Term

    原理

    Rabbit Anti-Mouse POLG (C-term) Antibody

    免疫原

    This POLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1120-1148 amino acids from the C-terminal region of human POLG.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, FC: 1:10-50, IF: 1:10-50, IHC: 1:10-50POLG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.460 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    POLG (Polymerase (DNA Directed), gamma (POLG))

    别名

    POLG

    背景

    Target Description: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

    Gene Symbol: POLG

    分子量

    139562 Da

    基因ID

    5428

    UniProt

    P54098
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