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Nanog 抗体 (AA 267-292)

This anti-Nanog antibody is a 兔 多克隆 antibody detecting Nanog in WB 和 IF. Suitable for 人.
产品编号 ABIN2798794
发货至: 中国

Quick Overview for Nanog 抗体 (AA 267-292) (ABIN2798794)

抗原

See all Nanog (NANOG) 抗体
Nanog (NANOG) (Nanog Homeobox (NANOG))

适用

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宿主

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克隆类型

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多克隆

标记

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This Nanog antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
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    AA 267-292

    原理

    Rabbit Anti-Human NANOG (S285) Antibody

    免疫原

    This NANOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-292 amino acids from human NANOG.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunofluorescence
    Recommended Dilutions
    WB: 1:1000, IF: 1:10-50Western blot analysis of NANOG (arrow) using rabbit NANOG Antibody (S285) . Nanog immunoreactivity is localized mainly to the nuclei and also to the cytoplasm.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.310 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    别名

    NANOG

    背景

    Target Description: NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.

    Gene Symbol: NANOG

    分子量

    34620 Da

    基因ID

    79923

    UniProt

    Q9H9S0

    途径

    Stem Cell Maintenance
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