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LIN28B 抗体 (Center)

The 兔 多克隆 anti-LIN28B antibody is suitable to detect LIN28B in samples from 人. It has been validated for WB, FACS, IHC 和 IF.
产品编号 ABIN2798789
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LIN28B 抗体 (Center) (ABIN2798789)

抗原

See all LIN28B 抗体
LIN28B (Lin-28 Homolog B (LIN28B))

适用

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宿主

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克隆类型

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多克隆

标记

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This LIN28B antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 95-128, Center

    原理

    Rabbit Anti-Human LIN28B (Center) Antibody

    免疫原

    This LIN28B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-128 amino acids from the Central region of human LIN28B.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry, Flow Cytometry, Immunofluorescence
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50, FC: 1:10-50, IF: 1:10-50Western blot analysis of anti-LIN28B Pab .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.500 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    LIN28B (Lin-28 Homolog B (LIN28B))

    别名

    LIN28B

    背景

    Target Description: Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains. Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene. Overexpression of LIN28B was noted in most HCC cell lines and clinical samples. A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver. Although predominantly localized in the cytoplasm, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells. Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation.

    Gene Symbol: LIN28B

    分子量

    27084 Da

    基因ID

    389421

    UniProt

    Q6ZN17
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