WHSC2 抗体 (Center)
Quick Overview for WHSC2 抗体 (Center) (ABIN2798759)
抗原
See all WHSC2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 251-279, Center
-
原理
- Rabbit Anti-Human WHSC2 (Center) Antibody
-
免疫原
- This WHSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the Central region of human WHSC2.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
Western Blot
Recommended Dilutions
WB: 1:1000WHSC2 Antibody (Center) . -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
-
别名
- WHSC2
-
背景
-
Target Description: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
Gene Symbol: NELFA
-
分子量
- 57277 Da
-
基因ID
- 7469
-
UniProt
- Q9H3P2
-
途径
- Chromatin Binding
抗原
-