WWOX 抗体 (C-Term)
Quick Overview for WWOX 抗体 (C-Term) (ABIN2798755)
抗原
See all WWOX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 369-396, C-Term
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原理
- Rabbit Anti-Mouse WWOX (C-term) Antibody
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免疫原
- This WWOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-396 amino acids from the C-terminal region of human WWOX.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000WWOX Antibody (C-term) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- WWOX (WW Domain Containing Oxidoreductase (WWOX))
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别名
- WWOX
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背景
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Target Description: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90 % identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
Gene Symbol: WWOX
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分子量
- 46677 Da
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基因ID
- 51741
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UniProt
- Q9NZC7
抗原
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