ORC2 抗体 (Center)
Quick Overview for ORC2 抗体 (Center) (ABIN2798616)
抗原
See all ORC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 208-237, Center
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原理
- Rabbit Anti-Human ORC2L (Center) Antibody
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免疫原
- This ORC2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human ORC2L.
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亚型
- Ig Fraction
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anti-Origin Recognition Complex Subunit 2 (ORC2) (AA 1-577) antibody
ORC2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E11-1G5 unconjugated
anti-Origin Recognition Complex Subunit 2 (ORC2) antibodyORC2 适用: 人 WB, IP 宿主: 大鼠 Monoclonal 3G6 unconjugated
anti-Origin Recognition Complex Subunit 2 (ORC2) antibodyORC2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex Subunit 2 (ORC2) (AA 382-431) antibodyORC2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex Subunit 2 (ORC2) (AA 458-577) antibodyORC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000ORC2L Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
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别名
- ORC2L
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背景
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Target Description: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.
Gene Symbol: ORC2
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分子量
- 65972 Da
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基因ID
- 4999
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UniProt
- Q13416
抗原
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