T-Bet 抗体 (N-Term)
Quick Overview for T-Bet 抗体 (N-Term) (ABIN2798591)
抗原
See all T-Bet 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 22-50, N-Term
-
原理
- Rabbit Anti-Human TBX21 (N-term) Antibody
-
免疫原
- This TBX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human TBX21.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
Immunofluorescence, Western Blot
Recommended Dilutions
IF: 1:10-50, WB: 1:1000Fluorescent image of A549 cell stained with TBX21 Antibody (N-term). -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.500 mg/mL
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- T-Bet
-
别名
- TBX21
-
背景
-
Target Description: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Gene Symbol: TBX21
-
分子量
- 58328 Da
-
基因ID
- 30009
-
UniProt
- Q9UL17
抗原
-