PITX2 抗体 (C-Term)
Quick Overview for PITX2 抗体 (C-Term) (ABIN2798528)
抗原
See all PITX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 122-151, C-Term
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原理
- Rabbit Anti-Human PITX2 (C-term) Antibody
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免疫原
- This PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the C-terminal region of human PITX2.
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亚型
- Ig Fraction
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应用备注
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Immunofluorescence, Western Blot
Recommended Dilutions
IF: 1:10-50, WB: 1:1000Fluorescent image of Hela cell stained with PITX2 Antibody (C-term) was detected using the purified Pab. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.430 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- PITX2 (Paired-Like Homeodomain 2 (PITX2))
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别名
- PITX2
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背景
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Target Description: Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.
Gene Symbol: PITX2
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分子量
- 35370 Da
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基因ID
- 5308
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UniProt
- Q99697
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途径
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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