SOCS6 抗体 (N-Term)
Quick Overview for SOCS6 抗体 (N-Term) (ABIN2798439)
抗原
See all SOCS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-69, N-Term
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原理
- Rabbit Anti-Human SOCS6 (N-term) Antibody
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免疫原
- This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50SOCS6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
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别名
- SOCS6
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背景
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Target Description: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Gene Symbol: SOCS6
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分子量
- 59528 Da
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基因ID
- 9306
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UniProt
- O14544
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途径
- JAK/STAT Signaling, Carbohydrate Homeostasis
抗原
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