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PUMA 抗体 (BH3 Domain)

The 兔 多克隆 anti-PUMA antibody is suitable to detect PUMA in samples from 人. It has been validated for WB, IHC, IF 和 FACS.
产品编号 ABIN2798057
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PUMA 抗体 (BH3 Domain) (ABIN2798057)

抗原

See all PUMA (BBC3) 抗体
PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PUMA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
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    AA 119-154, BH3 Domain

    原理

    Rabbit Anti-Human Puma BH3 Domain Antibody

    免疫原

    This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50, IF: 1:10-50, FC: 1:10-50Western blot analysis of anti-Puma BH3 domain Pab .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.000 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

    别名

    Puma

    背景

    Target Description: PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

    Gene Symbol: BBC3

    分子量

    20532 Da

    基因ID

    27113

    UniProt

    Q9BXH1

    途径

    p53 Pathway, Positive Regulation of Endopeptidase Activity
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