KREMEN2 抗体 (Center)
Quick Overview for KREMEN2 抗体 (Center) (ABIN2798011)
抗原
See all KREMEN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 248-276, Center
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原理
- Rabbit Anti-Human KREMEN2 (Center) Antibody
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免疫原
- This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000KREMEN2 Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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别名
- KREMEN2
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背景
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Target Description: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Gene Symbol: KREMEN2
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分子量
- 48849 Da
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基因ID
- 79412
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UniProt
- Q8NCW0
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途径
- WNT signaling
抗原
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