Surfactant Protein C 抗体 (N-Term)
Quick Overview for Surfactant Protein C 抗体 (N-Term) (ABIN2797711)
抗原
See all Surfactant Protein C (SFTPC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30, N-Term
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原理
- Rabbit Anti-Mouse SFTPC (N-term) Antibody
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免疫原
- This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.
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亚型
- Ig Fraction
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应用备注
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Immunofluorescence, Western Blot
Recommended Dilutions
IF: 1:25, WB: 1:1000Immunofluorescent analysis of Human lung tissues, using SFTPC Antibody (N-term) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.340 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- Surfactant Protein C (SFTPC)
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别名
- SFTPC
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背景
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Target Description: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Gene Symbol: SFTPC
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分子量
- 21053 Da
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基因ID
- 6440
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UniProt
- P11686
抗原
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