MLH1 抗体 (Center)
Quick Overview for MLH1 抗体 (Center) (ABIN2797430)
抗原
See all MLH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 452-480, Center
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原理
- Rabbit Anti-Human MLH1 (Center) Antibody
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免疫原
- This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50MLH1 Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.400 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- MLH1 (MutL Homolog 1 (MLH1))
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别名
- MLH1
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背景
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Target Description: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Gene Symbol: MLH1
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分子量
- 84601 Da
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基因ID
- 4292
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UniProt
- P40692
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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