CCR8 抗体 (C-Term)
Quick Overview for CCR8 抗体 (C-Term) (ABIN2797017)
抗原
See all CCR8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-317, C-Term
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原理
- Rabbit Anti-Human CCR8 (C-term) Antibody
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免疫原
- This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CCR8.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50CCR8 Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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别名
- CCR8
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背景
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Target Description: CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
Gene Symbol: CCR8
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分子量
- 40844 Da
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基因ID
- 1237
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UniProt
- P51685
抗原
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