KISS1 抗体 (Center)
Quick Overview for KISS1 抗体 (Center) (ABIN2796067)
抗原
See all KISS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 235-263, Center
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原理
- Rabbit Anti-Human KISS1R (Center) Antibody
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免疫原
- This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000KISS1R Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.650 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
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别名
- KISS1
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背景
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Target Description: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
Gene Symbol: KISS1R
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分子量
- 42586 Da
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基因ID
- 84634
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UniProt
- Q969F8
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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