PRKD3 抗体 (C-Term)
Quick Overview for PRKD3 抗体 (C-Term) (ABIN2795131)
抗原
See all PRKD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 860-890, C-Term
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原理
- Rabbit Anti-Human PKC nu (C-term) Antibody
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免疫原
- This PKC nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 860-890 amino acids from the C-terminal region of human PKC nu.
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亚型
- Ig Fraction
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anti-Protein Kinase D3 (PRKD3) (AA 352-384) antibody
PRKD3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D3 (PRKD3) (AA 1-100) antibodyPRKD3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G7 unconjugated
anti-Protein Kinase D3 (PRKD3) (AA 352-384) antibodyPRKD3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1047 unconjugated
anti-Protein Kinase D3 (PRKD3) (AA 860-890) antibodyPRKD3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D3 (PRKD3) (pSer41) antibodyPRKD3 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D3 (PRKD3) (AA 345-550) antibodyPRKD3 适用: 大鼠, 马 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D3 (PRKD3) (AA 326-510) antibodyPRKD3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D3 (PRKD3) (AA 576-832) antibodyPRKD3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D3 (PRKD3) (AA 860-890), (C-Term) antibodyPRKD3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1290 unconjugated
anti-Protein Kinase D3 (PRKD3) (N-Term) antibodyPRKD3 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-PKCnu C-term Pab antibodies. Lower panel, indirect immunofluorescence analysis of GFP-PKD3 fusion protein expression in Panc-1 cells by using 102-17077 and 102-17078 antibodies. Data courtesy of Dr. Osvaldo Rey, University of California Los Angeles.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.710 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- PRKD3 (Protein Kinase D3 (PRKD3))
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别名
- PKC nu
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背景
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Target Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
Gene Symbol: PRKD3
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分子量
- 100471 Da
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基因ID
- 23683
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UniProt
- O94806
抗原
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