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PRKD3 抗体 (AA 352-384)

This anti-PRKD3 antibody is a 兔 多克隆 antibody detecting PRKD3 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN2795130
发货至: 中国

Quick Overview for PRKD3 抗体 (AA 352-384) (ABIN2795130)

抗原

See all PRKD3 抗体
PRKD3 (Protein Kinase D3 (PRKD3))

适用

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宿主

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克隆类型

  • 81
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多克隆

标记

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This PRKD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 352-384

    原理

    Rabbit Anti-Human PKC nu Antibody

    免疫原

    This PKC-nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-384 amino acids from human PKC-nu.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-PKCnu Pab antibodies. Lower panel, indirect immunofluorescence analysis of GFP-PKD3 fusion protein expression in Panc-1 cells by using 102-17077 and 102-17078 antibodies. Data courtesy of Dr. Osvaldo Rey, University of California Los Angeles.
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.200 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    PRKD3 (Protein Kinase D3 (PRKD3))

    别名

    PKC nu

    背景

    Target Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

    Gene Symbol: PRKD3

    分子量

    100471 Da

    基因ID

    23683

    UniProt

    O94806
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