VEGFB 抗体 (Center)
Quick Overview for VEGFB 抗体 (Center) (ABIN2794873)
抗原
See all VEGFB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-139, Center
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原理
- Rabbit Anti-Human VEGFB (VEGF2) (Center) Antibody
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免疫原
- This VEGFB (VEGF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the Central region of human VEGFB (VEGF2).
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亚型
- Ig Fraction
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anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 100-200) antibody
VEGFB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 22-207) antibodyVEGFB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 22-207) antibodyVEGFB 适用: 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 22-137) antibodyVEGFB 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 22-207) antibodyVEGFB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (Internal Region) antibodyVEGFB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 25-207) antibodyVEGFB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 101-207) antibodyVEGFB 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) antibodyVEGFB 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor B (VEGFB) (AA 1-207) antibodyVEGFB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of VEGF2 (arrow) using rabbit polyclonal VEGF2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
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别名
- VEGFB
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背景
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Target Description: Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. VEGFB has structural similarities to VEGF and PIGF and is frequently co-expressed with VEGF. There are two alternatively spliced isoforms of VEGFB: VEGFB 167 and VEGFB 186. VEGFB 167, a highly basic heparin-binding protein, remains with the cell or extracellular matrix whereas, VEGFB 186 is readily secreted. VEGFB stimulates endothelial cell proliferation. VEGFB binds to the tyrosine kinase receptor VEGFR1 (flt1) and does not bind to VEGFR2. Vascular Endothelial Growth Factor B is widely expressed but is most abundant in heart, skeletal muscle, and pancreas. It has been suggested that VEGFB expression in human primary breast cancers is associated with lymph node metastasis. The genes that encode VEGFB have been mapped to chromosome 11q13.
Gene Symbol: VEGFB
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分子量
- 21602 Da
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基因ID
- 7423
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UniProt
- P49765
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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