电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

HAS2 抗体 (Center)

HAS2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2794747
发货至: 中国
  • 抗原 See all HAS2 抗体
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    抗原表位
    • 9
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 138-166, Center
    适用
    • 41
    • 24
    • 14
    宿主
    • 37
    • 13
    克隆类型
    • 37
    • 13
    多克隆
    标记
    • 15
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HAS2 antibody is un-conjugated
    应用范围
    • 30
    • 21
    • 12
    • 11
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    Rabbit Anti-Human HAS2 (Center) Antibody
    免疫原
    This HAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the Central region of human HAS2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product HAS2 Primary Antibody
  • 应用备注
    Western Blot, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100, FC: 1:10-50HAS2 Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    别名
    HAS2 (HAS2 产品)
    别名
    DG42 antibody, XHas2 antibody, Has2 antibody, hyaluronan synthase 2 antibody, hyaluronan synthase 2 S homeolog antibody, has2 antibody, HAS2 antibody, Has2 antibody, SHAS2 antibody, has2.S antibody
    背景

    Target Description: Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis, and human and murine hyaluronan synthase 1.

    Gene Symbol: HAS2

    分子量
    63566 Da
    基因ID
    3037
    UniProt
    Q92819
    途径
    Glycosaminoglycan Metabolic Process
You are here:
客服