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HAS2 抗体

HAS2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386495
发货至: 中国
  • 抗原 See all HAS2 抗体
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    适用
    人, 小鼠, 大鼠
    宿主
    • 38
    • 13
    克隆类型
    • 38
    • 13
    多克隆
    标记
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    This HAS2 antibody is un-conjugated
    应用范围
    • 31
    • 22
    • 14
    • 10
    • 9
    • 5
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    • 2
    • 1
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    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human HAS2/Hyaluronan synthase 2
    亚型
    IgG
    Top Product
    Discover our top product HAS2 Primary Antibody
  • 应用备注
    WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    别名
    Has2 (HAS2 产品)
    别名
    DG42 antibody, XHas2 antibody, Has2 antibody, hyaluronan synthase 2 antibody, hyaluronan synthase 2 S homeolog antibody, has2 antibody, HAS2 antibody, Has2 antibody, SHAS2 antibody, has2.S antibody
    背景

    Synonyms: HA synthase 2, has2, HAS2_HUMAN, Hyaluronan synthase 2, Hyaluronate synthase 2, Hyaluronic acid synthase 2.

    Background: HAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by i²-1,3 and i²-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesise high molecular-weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli suggesting distinct functional roles of the three proteins. HAS2 mRNA shows predominant expression in chondrocytes and cartilage. The human HAS2 gene maps to chromosome 8q24.12.

    途径
    Glycosaminoglycan Metabolic Process
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