Phospholamban 抗体 (pThr17)
Quick Overview for Phospholamban 抗体 (pThr17) (ABIN2794308)
抗原
See all Phospholamban (PLN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr17
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原理
- Rabbit Anti-Human Phospho-PLB(T17) Antibody
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免疫原
- This PLB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T17 of human PLB.
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亚型
- Ig Fraction
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应用备注
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Dot Blot
Recommended Dilutions
DB: 1:500
Dot blot analysis of anti-Phospho-PLB-T17 Phospho-specific Pab on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per ml. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- Phospholamban (PLN)
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别名
- PLB
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背景
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Target Description: Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases, whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
Gene Symbol: PLN
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分子量
- 6109 Da
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基因ID
- 5350
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UniProt
- P26678
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途径
- Negative Regulation of Transporter Activity
抗原
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