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SMAD4 抗体 (pThr277)

This anti-SMAD4 antibody is a 兔 多克隆 antibody detecting SMAD4 in IHC, IF 和 DB. Suitable for 人.
产品编号 ABIN2794149
发货至: 中国

Quick Overview for SMAD4 抗体 (pThr277) (ABIN2794149)

抗原

See all SMAD4 抗体
SMAD4 (SMAD Family Member 4 (SMAD4))

适用

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宿主

  • 80
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克隆类型

  • 62
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多克隆

标记

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This SMAD4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Dot Blot (DB)
  • 抗原表位

    • 13
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    pThr277

    原理

    Rabbit Anti-Human Phospho-SMAD4(T277) Antibody

    免疫原

    This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.

    亚型

    Ig Fraction
  • 应用备注

    Immunofluorescence, Dot Blot, Immunohistochemistry
    Recommended Dilutions
    IF: 1:10-50, DB: 1:500, IHC: 1:10-50Confocal immunofluorescent analysis of Phospho-SMAD4-T277 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    SMAD4 (SMAD Family Member 4 (SMAD4))

    别名

    SMAD4

    背景

    Target Description: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

    Gene Symbol: SMAD4

    分子量

    60439 Da

    基因ID

    4089

    UniProt

    Q13485

    途径

    Cell Division Cycle, Chromatin Binding, Autophagy
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