SMAD4 抗体 (pThr277)
Quick Overview for SMAD4 抗体 (pThr277) (ABIN2794149)
抗原
See all SMAD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr277
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原理
- Rabbit Anti-Human Phospho-SMAD4(T277) Antibody
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免疫原
- This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
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亚型
- Ig Fraction
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应用备注
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Immunofluorescence, Dot Blot, Immunohistochemistry
Recommended Dilutions
IF: 1:10-50, DB: 1:500, IHC: 1:10-50Confocal immunofluorescent analysis of Phospho-SMAD4-T277 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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别名
- SMAD4
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背景
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Target Description: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Gene Symbol: SMAD4
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分子量
- 60439 Da
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基因ID
- 4089
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UniProt
- Q13485
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途径
- Cell Division Cycle, Chromatin Binding, Autophagy
抗原
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