RAD9A 抗体 (pSer387)
Quick Overview for RAD9A 抗体 (pSer387) (ABIN2794137)
抗原
See all RAD9A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer387
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原理
- Rabbit Anti-Human Phospho-RAD9(S387) Antibody
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免疫原
- This RAD9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S387 of human RAD9.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100The anti-Phospho-Rad9-S387 Pab tissue lysateFormalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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别名
- RAD9
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背景
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Target Description: Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.
Gene Symbol: RAD9A
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分子量
- 42547 Da
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基因ID
- 5883
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UniProt
- Q99638
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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