USP39 抗体 (N-Term)
Quick Overview for USP39 抗体 (N-Term) (ABIN2793377)
抗原
See all USP39 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 108-139, N-Term
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原理
- Rabbit Anti-Human SAD1 (BRSK1) (N-term) Antibody
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免疫原
- This SAD1 (BRSK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-139 amino acids from the N-terminal region of human SAD1 (BRSK1).
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of anti-KIAA181 Pab was detected using the purified Pab. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.0 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- USP39 (Ubiquitin Specific Peptidase 39 (USP39))
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别名
- SAD1
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背景
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Target Description: BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv- or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell polarity regulator. The BRSK1 transcript is expressed ubiquitously with the highest levels of expression in brain and testis.
Gene Symbol: BRSK1
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分子量
- 85087 Da
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基因ID
- 84446
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UniProt
- Q8TDC3
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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