GIP 抗体 (N-Term)
Quick Overview for GIP 抗体 (N-Term) (ABIN2793043)
抗原
See all GIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-38, N-Term
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原理
- Rabbit Anti-Human GIPR (N-term) Antibody
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免疫原
- This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of GIPR antibody (N-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.000 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- GIP (Gastric Inhibitory Polypeptide (GIP))
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别名
- GIP
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背景
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Target Description: GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
Gene Symbol: GIPR
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分子量
- 53157 Da
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基因ID
- 2696
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UniProt
- P48546
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途径
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
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