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MNAT1 抗体 (N-Term)

This anti-MNAT1 antibody is a 兔 多克隆 antibody detecting MNAT1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, Pig 和 斑马鱼.
产品编号 ABIN2792694
发货至: 中国

Quick Overview for MNAT1 抗体 (N-Term) (ABIN2792694)

抗原

See all MNAT1 抗体
MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))

适用

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人, 小鼠, 大鼠, Cow, 犬, Pig, 斑马鱼

宿主

  • 42

克隆类型

  • 42
多克隆

标记

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This MNAT1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    DDQGCPRCKT TKYRNPSLKL MVNVCGHTLC ESCVDLLFVR GAGNCPECGT

    交叉反应

    牛, 犬, 小鸡, Fruit Fly (Drosophila melanogaster), 人, 小鼠, 猪, 大鼠

    预测反应

    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against MNAT1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human MNAT1
  • 应用备注

    WB Suggested Anti-MNAT1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: 721_B cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 309 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))

    别名

    MNAT1 / RNF66

    背景

    The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH, MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-498 AA053721.1 1-498 499-1372 BC000820.1 489-1362 1373-1388 BU620200.1 1-16 c
    Alias Symbols: MAT1, RNF66, TFB3, CAP35
    Protein Interaction Partner: RPA3, RPA2, RPA1, CDK7, CDK2, MBP, CTD, CCNH, NGFRAP1, UBC, NKX3-1, USP2, SUPT5H, POLR2A, GTF2H4, GTF2H3, GTF2H1, ERCC2, tat, TRIM39, TRIM34, TRIM17, TRIM2, ICK, TRIM31, RNF41, RNF7, TRIM26, MKRN3, TRIM21, MDM4, BRCA1, TRIML1, RNF32, TRIM9, TRIM5, XBP1P1,
    Protein Size: 309

    分子量

    36 kDa

    基因ID

    4331

    NCBI登录号

    NM_002431, NP_002422

    UniProt

    P51948

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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